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Multiple Sclerosis Treated with Bone Marrow Cells

5 December 2011 Please Comment
Multiple Sclerosis Treated with Bone Marrow Cells

“Safety and feasibility of autologous bone marrow cellular therapy in relapsing-progressive multiple sclerosis.”

Clin Pharmacol Ther. 2010 Jun;87(6):679-85

Rice CM et al.

SourceInstitute of Clinical Neurosciences, University of Bristol, Frenchay Hospital, Bristol, UK.

“In this phase I study, we assessed the safety and feasibility of intravenous, autologous bone marrow (BM) cell therapy, without immunosuppressive preconditioning, in six patients with clinically definite, relapsing-progressive multiple sclerosis (MS)”

“The lack of serious adverse effects and the suggestion of a beneficial effect in this small sample of patients with progressive disease justify conducting a larger phase II/III study to make a fuller assessment of the efficacy of mobilization of autologous BM in patients with MS”

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